人 JUP (NM_002230) cDNA克隆

Accession: NM_002230
基因名称: JUP
基因别名: DP3; PDGB; PKGB; CTNNG; DPIII; ARVD12
基因描述: Homo sapiens junction plakoglobin (JUP), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2238 (查看编码区序列)
翻译后氨基酸长度: 745 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
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G113753 人 JUP (NM_002230) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]