人 PAM (NM_001177306) cDNA克隆

基本信息

Accession: NM_001177306
基因名称: PAM
基因别名: PAL; PHM
基因描述: Homo sapiens peptidylglycine alpha-amidating monooxygenase (PAM), transcript variant 5, mRNA.
种属: Human
CDS区长度: 2922 (查看编码区序列)
翻译后氨基酸长度: 973 (查看氨基酸序列)
Transcript Variant: This variant (5) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in an isoform (e) that is 1 aa shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G113959 人 PAM (NM_001177306) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PAM (NM_000919) cDNA克隆 transcript variant 1
人 PAM (NM_138766) cDNA克隆 transcript variant 2
人 PAM (NM_138821) cDNA克隆 transcript variant 3
人 PAM (NM_138822) cDNA克隆 transcript variant 4
人 PAM (NM_001177306) cDNA克隆 transcript variant 5

基因简介

This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known. [provided by RefSeq, Jul 2008]

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