人 NLRP2 (NM_017852) cDNA克隆

Accession: NM_017852
基因名称: NLRP2
基因别名: NBS1; PAN1; NALP2; PYPAF2; CLR19.9
基因描述: Homo sapiens NLR family, pyrin domain containing 2 (NLRP2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3189 (查看编码区序列)
翻译后氨基酸长度: 1062 (查看氨基酸序列)
Transcript Variant: This variant (1) and variant 2 encode the same isoform (1).
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G114103 人 NLRP2 (NM_017852) cDNA克隆 pDONR223 2ug质粒 点击询价

NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]