人 PPFIA1 (NM_177423) cDNA克隆

基本信息

Accession: NM_177423
基因名称: PPFIA1
基因别名: LIP1; LIP.1; LIPRIN
基因描述: Homo sapiens protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 (PPFIA1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3558 (查看编码区序列)
翻译后氨基酸长度: 1185 (查看氨基酸序列)
Transcript Variant: This variant (1) differs in the 3' end, which includes a part of the coding region and 3' UTR, as compared to variant 2. The resulting protein (isoform a) has a distinct and shorter C-terminus, as compared to isoform b.

订购信息

产品编号 产品名称 载体 规格 价格
G114210 人 PPFIA1 (NM_177423) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PPFIA1 (NM_177423) cDNA克隆 transcript variant 1
人 PPFIA1 (NM_003626) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

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