人 TIE1 (NM_005424) cDNA克隆

基本信息

Accession: NM_005424
基因名称: TIE1
基因别名: TIE; JTK14
基因描述: Homo sapiens tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (TIE1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3417 (查看编码区序列)
翻译后氨基酸长度: 1138 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G114237 人 TIE1 (NM_005424) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TIE1 (NM_005424) cDNA克隆 transcript variant 1
人 TIE1 (NM_001253357) cDNA克隆 transcript variant 2

基因简介

This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

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