人 ZFYVE16 (NM_001284237) cDNA克隆

Accession: NM_001284237
基因名称: ZFYVE16
基因别名: PPP1R69
基因描述: Homo sapiens zinc finger, FYVE domain containing 16 (ZFYVE16), transcript variant 4, mRNA.
种属: Human
CDS区长度: 2430 (查看编码区序列)
翻译后氨基酸长度: 809 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks several exons in the 3' coding region and contains a 3' terminal exon that extends past a splice site that is used in variant 1 resulting in an early stop codon, and a different 3' UTR, compared to variant 1. The encoded protein (isoform b) has a distinct C-terminus and is shorter than isoform a.
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G114243 人 ZFYVE16 (NM_001284237) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor-beta signaling pathway and is involved in positive and negative feedback regulation of the bone morphogenetic protein signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]