人 NT5C (NM_001252377) cDNA克隆

Accession: NM_001252377
基因名称: NT5C
基因别名: DNT; cdN; DNT1; P5N2; PN-I; PN-II; UMPH2; dNT-1
基因描述: Homo sapiens 5', 3'-nucleotidase, cytosolic (NT5C), transcript variant 2, mRNA.
种属: Human
CDS区长度: 486 (查看编码区序列)
翻译后氨基酸长度: 161 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame coding exon, and uses an alternate in-frame acceptor splice site at the 3' terminal exon compared to variant 1. This results in a shorter isoform (2) missing an internal protein segment compared to isoform 1.
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G114403 人 NT5C (NM_001252377) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]