人 DYNLRB1 (NM_001281727) cDNA克隆

基本信息

Accession: NM_001281727
基因名称: DYNLRB1
基因别名: BLP; BITH; DNCL2A; DNLC2A; ROBLD1
基因描述: Homo sapiens dynein, light chain, roadblock-type 1 (DYNLRB1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 192 (查看编码区序列)
翻译后氨基酸长度: 63 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in its 5' UTR and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, and 4 encode the same isoform.

订购信息

产品编号 产品名称 载体 规格 价格
G114463 人 DYNLRB1 (NM_001281727) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 DYNLRB1 (NM_014183) cDNA克隆 transcript variant 1
人 DYNLRB1 (NM_177953) cDNA克隆 transcript variant 2
人 DYNLRB1 (NM_001281727) cDNA克隆 transcript variant 3
人 DYNLRB1 (NM_001281728) cDNA克隆 transcript variant 4
人 DYNLRB1 (NM_001281729) cDNA克隆 transcript variant 5

基因简介

This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013]

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