人 NCBP2 (NM_001042540) cDNA克隆

Accession: NM_001042540
基因名称: NCBP2
基因别名: CBC2; NIP1; CBP20; PIG55
基因描述: Homo sapiens nuclear cap binding protein subunit 2, 20kDa (NCBP2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 312 (查看编码区序列)
翻译后氨基酸长度: 103 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame combination of splice sites in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 2).
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G114544 人 NCBP2 (NM_001042540) cDNA克隆 pDONR223 2ug质粒 点击询价

The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]