The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
人 SERPINB1 (NM_030666) cDNA克隆
| Accession: | NM_030666 |
|---|---|
| 基因名称: | SERPINB1 |
| 基因别名: | EI; LEI; PI2; MNEI; PI-2; M/NEI; ELANH2 |
| 基因描述: | Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 1 (SERPINB1), transcript variant 1, mRNA. |
| 种属: | Human |
| CDS区长度: | 1140 (查看编码区序列) |
| 翻译后氨基酸长度: | 379 (查看氨基酸序列) |
| Transcript Variant: | This variant (1) encodes the functional protein. |
| 人 SERPINB1 (NM_030666) cDNA克隆 | transcript variant 1 |
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