人 AZIN1 (NM_148174) cDNA克隆

Accession: NM_148174
基因名称: AZIN1
基因别名: OAZI; OAZIN; ODC1L
基因描述: Homo sapiens antizyme inhibitor 1 (AZIN1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1347 (查看编码区序列)
翻译后氨基酸长度: 448 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks a segment of the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
产品编号 产品名称 载体 规格 价格
G114977 人 AZIN1 (NM_148174) cDNA克隆 pDONR223 2ug质粒 点击询价

Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein encoded by this gene is highly similar to ODC. It binds to ODC antizyme and stabilizes ODC, thus inhibiting antizyme-mediated ODC degradation. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]