人 H2AFY (NM_138609) cDNA克隆

Accession: NM_138609
基因名称: H2AFY
基因别名: H2A.y; H2A/y; H2AFJ; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2
基因描述: Homo sapiens H2A histone family, member Y (H2AFY), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1110 (查看编码区序列)
翻译后氨基酸长度: 369 (查看氨基酸序列)
Transcript Variant: This variant (1) has multiple differences in the coding region, compared to variant 3. This results in a shorter protein (isoform 1) with a distinct segment in the middle of its coding region, compared to isoform 3.
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G114984 人 H2AFY (NM_138609) cDNA克隆 pDONR223 2ug质粒 点击询价

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]