人 SRC (NM_005417) cDNA克隆

Accession: NM_005417
基因名称: SRC
基因别名: ASV; SRC1; c-SRC; p60-Src
基因描述: Homo sapiens v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (SRC), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1611 (查看编码区序列)
翻译后氨基酸长度: 536 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
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G115089 人 SRC (NM_005417) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]