人 NR4A1 (NM_001202233) cDNA克隆

基本信息

Accession: NM_001202233
基因名称: NR4A1
基因别名: HMR; N10; TR3; NP10; GFRP1; NAK-1; NGFIB; NUR77
基因描述: Homo sapiens nuclear receptor subfamily 4, group A, member 1 (NR4A1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1836 (查看编码区序列)
翻译后氨基酸长度: 611 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and contains an alternate exon in the 5' coding region compared to variant 1. These differences cause translation initiation at an upstream AUG and result in a protein (isoform 2) with a longer N-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G115265 人 NR4A1 (NM_001202233) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NR4A1 (NM_002135) cDNA克隆 transcript variant 1
人 NR4A1 (NM_173157) cDNA克隆 transcript variant 2
人 NR4A1 (NM_001202233) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

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