人 PRKAA1 (NM_006251) cDNA克隆

基本信息

Accession: NM_006251
基因名称: PRKAA1
基因别名: AMPK; AMPKa1
基因描述: Homo sapiens protein kinase, AMP-activated, alpha 1 catalytic subunit (PRKAA1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1680 (查看编码区序列)
翻译后氨基酸长度: 559 (查看氨基酸序列)
Transcript Variant: This variant (1) appears to represent the more predominantly expressed transcript. It lacks an in-frame coding exon compared to variant 2. The resulting isoform (1) lacks an internal segment, as compared to isoform 2.

订购信息

产品编号 产品名称 载体 规格 价格
G115512 人 PRKAA1 (NM_006251) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PRKAA1 (NM_006251) cDNA克隆 transcript variant 1
人 PRKAA1 (NM_206907) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

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