人 GK (NM_001205019) cDNA克隆

基本信息

Accession: NM_001205019
基因名称: GK
基因别名: GK1; GKD
基因描述: Homo sapiens glycerol kinase (GK), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1680 (查看编码区序列)
翻译后氨基酸长度: 559 (查看氨基酸序列)
Transcript Variant: This variant (4) contains an additional in-frame coding exon at the 3' end compared to variant 1. This results in a longer isoform (d) with a protein segment not found in isoform a. The exon combination used for this variant is inferred, however, there is cross-species evidence for the existence of such a variant in mouse (AK044308:BAC31861) and cow (BC122692.1:AAI22693.1).

订购信息

产品编号 产品名称 载体 规格 价格
G115553 人 GK (NM_001205019) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GK (NM_203391) cDNA克隆 transcript variant 1
人 GK (NM_000167) cDNA克隆 transcript variant 2
人 GK (NM_001128127) cDNA克隆 transcript variant 3
人 GK (NM_001205019) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]