人 GNAL (NM_182978) cDNA克隆

Accession: NM_182978
基因名称: GNAL
基因别名: DYT25
基因描述: Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (GNAL), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1377 (查看编码区序列)
翻译后氨基酸长度: 458 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
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G115569 人 GNAL (NM_182978) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. This protein couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in this gene have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]