人 CDKL3 (NM_016508) cDNA克隆

Accession: NM_016508
基因名称: CDKL3
基因别名: NKIAMRE
基因描述: Homo sapiens cyclin-dependent kinase-like 3 (CDKL3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1368 (查看编码区序列)
翻译后氨基酸长度: 455 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 3' UTR and has multiple coding region differences, compared to variant 1. The encoded protein (isoform 2) has a shorter and distinct C-terminus, compared to isoform 1.
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G115757 人 CDKL3 (NM_016508) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]