人 PPHLN1 (NM_016488) cDNA克隆

Accession: NM_016488
基因名称: PPHLN1
基因别名: HSPC206; HSPC232
基因描述: Homo sapiens periphilin 1 (PPHLN1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1377 (查看编码区序列)
翻译后氨基酸长度: 458 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G115976 人 PPHLN1 (NM_016488) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]