NOP16 is transcriptionally regulated by c-Myc (MYC; MIM 190080), upregulated in breast cancer, and overexpression is associated with poor patient survival (Butt et al., 2008).[supplied by OMIM, Jun 2009]
| Accession: | NM_016391 |
|---|---|
| 基因名称: | NOP16 |
| 基因别名: | HSPC111; HSPC185 |
| 基因描述: | Homo sapiens NOP16 nucleolar protein (NOP16), transcript variant 3, mRNA. |
| 种属: | Human |
| CDS区长度: | 537 (查看编码区序列) |
| 翻译后氨基酸长度: | 178 (查看氨基酸序列) |
| Transcript Variant: | This variant (3) uses an alternate splice junction at the 5' end of the last exon compared to variant 1, that causes a frameshift. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1. |
| 人 NOP16 (NM_001256539) cDNA克隆 | transcript variant 1 |
| 人 NOP16 (NM_001256540) cDNA克隆 | transcript variant 2 |
| 人 NOP16 (NM_016391) cDNA克隆 | transcript variant 3 |
NOP16 is transcriptionally regulated by c-Myc (MYC; MIM 190080), upregulated in breast cancer, and overexpression is associated with poor patient survival (Butt et al., 2008).[supplied by OMIM, Jun 2009]