人 ARNT (NM_001286036) cDNA克隆

基本信息

Accession: NM_001286036
基因名称: ARNT
基因别名: HIF1B; TANGO; bHLHe2; HIF1BETA; HIF-1beta; HIF1-beta; HIF-1-beta
基因描述: Homo sapiens aryl hydrocarbon receptor nuclear translocator (ARNT), transcript variant 6, mRNA.
种属: Human
CDS区长度: 2364 (查看编码区序列)
翻译后氨基酸长度: 787 (查看氨基酸序列)
Transcript Variant: This variant (6) uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (6) is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G116159 人 ARNT (NM_001286036) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ARNT (NM_001668) cDNA克隆 transcript variant 1
人 ARNT (NM_178427) cDNA克隆 transcript variant 3
人 ARNT (NM_001197325) cDNA克隆 transcript variant 4
人 ARNT (NM_001286035) cDNA克隆 transcript variant 5
人 ARNT (NM_001286036) cDNA克隆 transcript variant 6

基因简介

This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]

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