KIFC3 belongs to the large superfamily of kinesins, molecular motors that use the energy of ATP hydrolysis to translocate cargoes along microtubules. Members share extensive homology within a globular domain containing the microtubule- and ATP-binding sites and have a coiled-coil stalk domain that mediates oligomerization. Different kinesin family members participate in specific and diverse motile processes, such as cell division, organelle transport, and nuclear movement (Hoang et al., 1998 [PubMed 9782090]).[supplied by OMIM, Mar 2009]
人 KIFC3 (NM_001130100) cDNA克隆
| Accession: | NM_001130100 |
|---|---|
| 基因名称: | KIFC3 |
| 基因描述: | Homo sapiens kinesin family member C3 (KIFC3), transcript variant 2, mRNA. |
| 种属: | Human |
| CDS区长度: | 2481 (查看编码区序列) |
| 翻译后氨基酸长度: | 826 (查看氨基酸序列) |
| Transcript Variant: | This variant (2) has an additional exon, which includes a stop codon, in the 3' region, as compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, as compared to isoform 1. |
| 人 KIFC3 (NM_005550) cDNA克隆 | transcript variant 1 |
| 人 KIFC3 (NM_001130100) cDNA克隆 | transcript variant 2 |
| 人 KIFC3 (NM_001130099) cDNA克隆 | transcript variant 3 |
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