人 UPP1 (NM_001287428) cDNA克隆

基本信息

Accession: NM_001287428
基因名称: UPP1
基因别名: UP; UPP; UPASE; UDRPASE
基因描述: Homo sapiens uridine phosphorylase 1 (UPP1), transcript variant 4, mRNA.
种属: Human
CDS区长度: 522 (查看编码区序列)
翻译后氨基酸长度: 173 (查看氨基酸序列)
Transcript Variant: This variant (4) differs in the 5' UTR, lacks three exons in the 5' coding region and initiates translation at an alternate start codon, compared to variant 3. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a. Variants 4, 5 and 6 all encode isoform b.

订购信息

产品编号 产品名称 载体 规格 价格
G116474 人 UPP1 (NM_001287428) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 UPP1 (NM_003364) cDNA克隆 transcript variant 1
人 UPP1 (NM_001287426) cDNA克隆 transcript variant 3
人 UPP1 (NM_001287428) cDNA克隆 transcript variant 4
人 UPP1 (NM_001287429) cDNA克隆 transcript variant 5
人 UPP1 (NM_001287430) cDNA克隆 transcript variant 6

基因简介

The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA (Watanabe and Uchida, 1995 [PubMed 7488099]).[supplied by OMIM, Aug 2009]

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