人 KLK8 (NM_007196) cDNA克隆

Accession: NM_007196
基因名称: KLK8
基因别名: NP; HNP; NRPN; PRSS19; TADG14
基因描述: Homo sapiens kallikrein-related peptidase 8 (KLK8), transcript variant 1, mRNA.
种属: Human
CDS区长度: 783 (查看编码区序列)
翻译后氨基酸长度: 260 (查看氨基酸序列)
Transcript Variant: This variant (1, also known as T1) uses an alternate splice site in the 5' coding region, compared to variant 2. It encodes isoform 1, which is shorter than isoform 2.
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G116483 人 KLK8 (NM_007196) cDNA克隆 pDONR223 2ug质粒 点击询价

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]