人 KATNA1 (NM_001204076) cDNA克隆

Accession: NM_001204076
基因名称: KATNA1
基因描述: Homo sapiens katanin p60 (ATPase containing) subunit A 1 (KATNA1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 936 (查看编码区序列)
翻译后氨基酸长度: 311 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks two alternate in-frame exons in the central coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.
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G116628 人 KATNA1 (NM_001204076) cDNA克隆 pDONR223 2ug质粒 点击询价

Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2011]