人 ST3GAL3 (NM_174965) cDNA克隆

Accession: NM_174965
基因名称: ST3GAL3
基因别名: ST3N; MRT12; SIAT6; EIEE15; ST3GALII; ST3GalIII
基因描述: Homo sapiens ST3 beta-galactoside alpha-2,3-sialyltransferase 3 (ST3GAL3), transcript variant 3, mRNA.
种属: Human
CDS区长度: 513 (查看编码区序列)
翻译后氨基酸长度: 170 (查看氨基酸序列)
Transcript Variant: This variant (3) has multiple differences in the coding region, one of which results in a frameshift compared to variant 1. The resulting isoform (c, also called A7) has a distinct C-terminus and is shorter compared to isoform a.
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G116641 人 ST3GAL3 (NM_174965) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with autosomal recessive nonsymdromic mental retardation-12 (MRT12). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]