人 USP15 (NM_006313) cDNA克隆

Accession: NM_006313
基因名称: USP15
基因别名: UNPH4; UNPH-2
基因描述: Homo sapiens ubiquitin specific peptidase 15 (USP15), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2859 (查看编码区序列)
翻译后氨基酸长度: 952 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
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G117176 人 USP15 (NM_006313) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011]