人 DPYSL2 (NM_001244604) cDNA克隆

基本信息

Accession: NM_001244604
基因名称: DPYSL2
基因别名: DRP2; N2A3; CRMP2; DRP-2; ULIP2; CRMP-2; DHPRP2; ULIP-2
基因描述: Homo sapiens dihydropyrimidinase-like 2 (DPYSL2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1611 (查看编码区序列)
翻译后氨基酸长度: 536 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G117469 人 DPYSL2 (NM_001244604) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 DPYSL2 (NM_001197293) cDNA克隆 transcript variant 1
人 DPYSL2 (NM_001386) cDNA克隆 transcript variant 2
人 DPYSL2 (NM_001244604) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

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