人 ELK1 (NM_001114123) cDNA克隆

基本信息

Accession: NM_001114123
基因名称: ELK1
基因描述: Homo sapiens ELK1, member of ETS oncogene family (ELK1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1287 (查看编码区序列)
翻译后氨基酸长度: 428 (查看氨基酸序列)
Transcript Variant: This variant (1, also known as 5'UTR long or 5'UTRL) represents the longest transcript and encodes the longer isoform (a). Both variants 1 and 2 encode isoform a. Delayed translational reinitiation from an alternative downstream start codon, AUG sElk-1, can also result in a shorter isoform (sELK-1), as described in PMID:22354998.

订购信息

产品编号 产品名称 载体 规格 价格
G117496 人 ELK1 (NM_001114123) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ELK1 (NM_001114123) cDNA克隆 transcript variant 1
人 ELK1 (NM_005229) cDNA克隆 transcript variant 2
人 ELK1 (NM_001257168) cDNA克隆 transcript variant 3

基因简介

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012]

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