人 NOB1 (NM_014062) cDNA克隆

基本信息

Accession: NM_014062
基因名称: NOB1
基因别名: ART-4; NOB1P; MST158; MSTP158; PSMD8BP1
基因描述: Homo sapiens NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) (NOB1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1239 (查看编码区序列)
翻译后氨基酸长度: 412 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.

订购信息

产品编号 产品名称 载体 规格 价格
G117559 人 NOB1 (NM_014062) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NOB1 (NM_014062) cDNA克隆 transcript variant 1

基因简介

In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010]

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