人 RPS6KB1 (NM_001272043) cDNA克隆

基本信息

Accession: NM_001272043
基因名称: RPS6KB1
基因别名: S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha
基因描述: Homo sapiens ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1356 (查看编码区序列)
翻译后氨基酸长度: 451 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 3' UTR and uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. This variant can initiate translation from two alternate in-frame AUG start codons. The isoform represented in this RefSeq (c) is derived from the first AUG start codon. It has a distinct C-terminus, and is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G117563 人 RPS6KB1 (NM_001272043) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RPS6KB1 (NM_003161) cDNA克隆 transcript variant 1
人 RPS6KB1 (NM_001272060) cDNA克隆 transcript variant 1
人 RPS6KB1 (NM_001272042) cDNA克隆 transcript variant 2
人 RPS6KB1 (NM_001272043) cDNA克隆 transcript variant 3
人 RPS6KB1 (NM_001272044) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]

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