人 TAC3 (NM_001178054) cDNA克隆

Accession: NM_001178054
基因名称: TAC3
基因别名: NKB; HH10; NKNB; PRO1155; ZNEUROK1
基因描述: Homo sapiens tachykinin 3 (TAC3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 312 (查看编码区序列)
翻译后氨基酸长度: 103 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
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G117599 人 TAC3 (NM_001178054) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]