人 SIRPB1 (NM_001083910) cDNA克隆

基本信息

Accession: NM_001083910
基因名称: SIRPB1
基因别名: CD172b; SIRP-BETA-1
基因描述: Homo sapiens signal-regulatory protein beta 1 (SIRPB1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 546 (查看编码区序列)
翻译后氨基酸长度: 181 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks two in-frame coding exons in the 3' region compared to variant 1. The resulting isoform (2) lacks an internal segment compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G117607 人 SIRPB1 (NM_001083910) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SIRPB1 (NM_006065) cDNA克隆 transcript variant 1
人 SIRPB1 (NM_001083910) cDNA克隆 transcript variant 2
人 SIRPB1 (NM_001135844) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

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