人 LRR1 (NM_203467) cDNA克隆

基本信息

Accession: NM_203467
基因名称: LRR1
基因别名: LRR-1; PPIL5; 4-1BBLRR
基因描述: Homo sapiens leucine rich repeat protein 1 (LRR1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 441 (查看编码区序列)
翻译后氨基酸长度: 146 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks a coding region exon which leads to a frameshift, compared to variant 1. The resulting isoform (3) has a distinct and shorter C-terminus, as compared to isoform 1. Isoform 3 has also been named LRR-1b.

订购信息

产品编号 产品名称 载体 规格 价格
G117702 人 LRR1 (NM_203467) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 LRR1 (NM_152329) cDNA克隆 transcript variant 1
人 LRR1 (NM_203467) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]

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