人 CABP1 (NM_004276) cDNA克隆

Accession: NM_004276
基因名称: CABP1
基因别名: CALBRAIN; HCALB_BR
基因描述: Homo sapiens calcium binding protein 1 (CABP1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 504 (查看编码区序列)
翻译后氨基酸长度: 167 (查看氨基酸序列)
Transcript Variant: This variant (2) has an alternate 5' exon, as compared to variant 3. The encoded isoform 2 has a distinct and shorter N-terminus, as compared to isoform 3.
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G117730 人 CABP1 (NM_004276) cDNA克隆 pDONR223 2ug质粒 点击询价

Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This gene encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin. The protein encoded by this gene regulates the gating of voltage-gated calcium ion channels. This protein inhibits calcium-dependent inactivation and supports calcium-dependent facilitation of ion channels containing voltage-dependent L-type calcium channel subunit alpha-1C. This protein also regulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors, P/Q-type voltage-gated calcium channels, and transient receptor potential channel TRPC5. This gene is predominantly expressed in retina and brain. Alternative splicing results in multiple transcript variants encoding disinct isoforms. [provided by RefSeq, Jul 2012]