人 KAZN (NM_001018001) cDNA克隆

Accession: NM_001018001
基因名称: KAZN
基因别名: KAZ; RP1-21O18.1
基因描述: Homo sapiens kazrin, periplakin interacting protein (KAZN), transcript variant C, mRNA.
种属: Human
CDS区长度: 984 (查看编码区序列)
翻译后氨基酸长度: 327 (查看氨基酸序列)
Transcript Variant: This variant (C) has multiple differences in the 5' and 3' termini, compared to variant E. These differences result in an isoform (C) with a shorter N-terminus and a shorter and distince C-terminus, compared to isoform E. Variants C and D encode the same protein.
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G117818 人 KAZN (NM_001018001) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desmoplakin and the cytolinker protein periplakin. In general, this protein localizes to the nucleus, desmosomes, cell membrane, and cortical actin-based structures. Some isoforms of this protein also associate with microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity has not been verified. [provided by RefSeq, Aug 2011]