人 GYPC (NM_001256584) cDNA克隆

基本信息

Accession: NM_001256584
基因名称: GYPC
基因别名: GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2'
基因描述: Homo sapiens glycophorin C (Gerbich blood group) (GYPC), transcript variant 3, mRNA.
种属: Human
CDS区长度: 324 (查看编码区序列)
翻译后氨基酸长度: 107 (查看氨基酸序列)
Transcript Variant: This variant (3) has an additional exon, compared to variant 1. This variant represents translation initiation at a downstream AUG compared to variant 1; the 5'-most initiation codon, as used in variant 1, is associated with a weak Kozak sequence and a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the downstream AUG, which is associated with a strong Kozak sequence. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G117874 人 GYPC (NM_001256584) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GYPC (NM_002101) cDNA克隆 transcript variant 1
人 GYPC (NM_016815) cDNA克隆 transcript variant 2
人 GYPC (NM_001256584) cDNA克隆 transcript variant 3

基因简介

Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

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