人 FUS (NM_004960) cDNA克隆

Accession: NM_004960
基因名称: FUS
基因别名: TLS; ALS6; ETM4; FUS1; POMP75; HNRNPP2
基因描述: Homo sapiens fused in sarcoma (FUS), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1581 (查看编码区序列)
翻译后氨基酸长度: 526 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G118126 人 FUS (NM_004960) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]