人 DPM3 (NM_153741) cDNA克隆

Accession: NM_153741
基因名称: DPM3
基因别名: CDG1O
基因描述: Homo sapiens dolichyl-phosphate mannosyltransferase polypeptide 3 (DPM3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 279 (查看编码区序列)
翻译后氨基酸长度: 92 (查看氨基酸序列)
Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR and 5' coding region, compared to variant 1. This results in translation initiation from a downstream ATG and an isoform (2) with a shorter N-terminus compared to isoform 1.
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G118134 人 DPM3 (NM_153741) cDNA克隆 pDONR223 2ug质粒 点击询价

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex. [provided by RefSeq, Jul 2008]