人 CENPM (NM_001110215) cDNA克隆

Accession: NM_001110215
基因名称: CENPM
基因别名: PANE1; CENP-M; C22orf18; bK250D10.2
基因描述: Homo sapiens centromere protein M (CENPM), transcript variant 3, mRNA.
种属: Human
CDS区长度: 177 (查看编码区序列)
翻译后氨基酸长度: 58 (查看氨基酸序列)
Transcript Variant: This variant (3) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and an isoform (c) with a shorter N-terminus compared to isoform a.
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G118169 人 CENPM (NM_001110215) cDNA克隆 pDONR223 2ug质粒 点击询价

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]