人 ALDOA (NM_001243177) cDNA克隆

基本信息

Accession: NM_001243177
基因名称: ALDOA
基因别名: ALDA; GSD12
基因描述: Homo sapiens aldolase A, fructose-bisphosphate (ALDOA), transcript variant 6, mRNA.
种属: Human
CDS区长度: 1257 (查看编码区序列)
翻译后氨基酸长度: 418 (查看氨基酸序列)
Transcript Variant: This variant (6) differs in the 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The resulting isoform (2) is longer at the N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G118197 人 ALDOA (NM_001243177) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ALDOA (NM_000034) cDNA克隆 transcript variant 1
人 ALDOA (NM_184041) cDNA克隆 transcript variant 2
人 ALDOA (NM_184043) cDNA克隆 transcript variant 3
人 ALDOA (NM_001127617) cDNA克隆 transcript variant 4
人 ALDOA (NM_001243177) cDNA克隆 transcript variant 6

基因简介

The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Aug 2011]

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