人 KCNIP2 (NM_173197) cDNA克隆

Accession: NM_173197
基因名称: KCNIP2
基因别名: KCHIP2
基因描述: Homo sapiens Kv channel interacting protein 2 (KCNIP2), transcript variant 7, mRNA.
种属: Human
CDS区长度: 555 (查看编码区序列)
翻译后氨基酸长度: 184 (查看氨基酸序列)
Transcript Variant: This variant (7), also known as KChIP2.5, lacks four coding segments: two consecutive in the 5' region, one in the middle, and one at the 3' end, but has an alternate segment at the 3' end, as compared to variant 1. The alternate segment contains the stop codon. Therefore, isoform 7 has a distinct C-terminus and is shorter than isoform 1.
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G118281 人 KCNIP2 (NM_173197) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene. [provided by RefSeq, Jul 2008]