人 GGA1 (NM_001001560) cDNA克隆

Accession: NM_001001560
基因名称: GGA1
基因描述: Homo sapiens golgi-associated, gamma adaptin ear containing, ARF binding protein 1 (GGA1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1659 (查看编码区序列)
翻译后氨基酸长度: 552 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks 2 in-frame exons in the coding region, as compared to variant 1. The encoded isoform 2 thus lacks an internal segment, as compared to isoform 1.
产品编号 产品名称 载体 规格 价格
G118447 人 GGA1 (NM_001001560) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]