人 ODC1 (NM_001287188) cDNA克隆

Accession: NM_001287188
基因名称: ODC1
基因别名: ODC
基因描述: Homo sapiens ornithine decarboxylase 1 (ODC1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 999 (查看编码区序列)
翻译后氨基酸长度: 332 (查看氨基酸序列)
Transcript Variant: This variant (2) has an alternate splice site, which results in translation initiation at a downstream AUG start codon, compared to variant 1. The resulting isoform (2) has a shorter N-termius, compared to isoform 1.
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G118480 人 ODC1 (NM_001287188) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013]