LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., 2007 [PubMed 18042720]; Touvier et al., 2009 [PubMed 19907080]).[supplied by OMIM, Jul 2010]
人 LEPROT (NM_017526) cDNA克隆
| Accession: | NM_017526 |
|---|---|
| 基因名称: | LEPROT |
| 基因别名: | LEPR; VPS55; OBRGRP; OB-RGRP |
| 基因描述: | Homo sapiens leptin receptor overlapping transcript (LEPROT), transcript variant 1, mRNA. |
| 种属: | Human |
| CDS区长度: | 396 (查看编码区序列) |
| 翻译后氨基酸长度: | 131 (查看氨基酸序列) |
| Transcript Variant: | This variant (1) is dominant and encodes the shorter isoform (1). |
| 人 LEPROT (NM_017526) cDNA克隆 | transcript variant 1 |
| 人 LEPROT (NM_001198681) cDNA克隆 | transcript variant 2 |
| 人 LEPROT (NM_001198683) cDNA克隆 | transcript variant 3 |
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