人 TDGF1 (NM_001174136) cDNA克隆

Accession: NM_001174136
基因名称: TDGF1
基因别名: CR; CRGF; CRIPTO
基因描述: Homo sapiens teratocarcinoma-derived growth factor 1 (TDGF1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 519 (查看编码区序列)
翻译后氨基酸长度: 172 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and lacks a portion of the 5' coding region, compared to variant 1. These differences causes translation initiation at a downstream AUG and results an isoform (2) with a shorter N-terminus, compared to isoform 1.
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G118661 人 TDGF1 (NM_001174136) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]