人 IL37 (NM_173203) cDNA克隆

Accession: NM_173203
基因名称: IL37
基因别名: FIL1; FIL1Z; IL-1H; IL-37; IL1F7; IL1H4; IL-1F7; IL-1H4; IL1RP1; IL-1RP1; FIL1(ZETA)
基因描述: Homo sapiens interleukin 37 (IL37), transcript variant 3, mRNA.
种属: Human
CDS区长度: 474 (查看编码区序列)
翻译后氨基酸长度: 157 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks two consecutive exons but maintains the reading frame, compared to variant 1, resulting an isoform (3) that lacks an internal region, as compared to isoform 1.
产品编号 产品名称 载体 规格 价格
G118722 人 IL37 (NM_173203) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]