人 AGER (NM_001206934) cDNA克隆

基本信息

Accession: NM_001206934
基因名称: AGER
基因别名: RAGE
基因描述: Homo sapiens advanced glycosylation end product-specific receptor (AGER), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1092 (查看编码区序列)
翻译后氨基酸长度: 363 (查看氨基酸序列)
Transcript Variant: This variant (4, also known as RAGE_v6) lacks the penultimate coding exon, and uses alternate donor splice sites at two internal coding exons compared to variant 1. This results in a frame-shift and a shorter isoform (4) with a distinct C-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G118815 人 AGER (NM_001206934) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 AGER (NM_001136) cDNA克隆 transcript variant 1
人 AGER (NM_001206929) cDNA克隆 transcript variant 2
人 AGER (NM_001206932) cDNA克隆 transcript variant 3
人 AGER (NM_001206934) cDNA克隆 transcript variant 4
人 AGER (NM_001206936) cDNA克隆 transcript variant 5
人 AGER (NM_001206940) cDNA克隆 transcript variant 6
人 AGER (NM_172197) cDNA克隆 transcript variant 7
人 AGER (NM_001206954) cDNA克隆 transcript variant 8
人 AGER (NM_001206966) cDNA克隆 transcript variant 9

基因简介

The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]

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