人 TERF1 (NM_003218) cDNA克隆

Accession: NM_003218
基因名称: TERF1
基因别名: TRF; PIN2; TRF1; TRBF1; t-TRF1; hTRF1-AS
基因描述: Homo sapiens telomeric repeat binding factor (NIMA-interacting) 1 (TERF1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1260 (查看编码区序列)
翻译后氨基酸长度: 419 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1.
产品编号 产品名称 载体 规格 价格
G119068 人 TERF1 (NM_003218) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq, Jul 2008]