人 NCR3 (NM_001145466) cDNA克隆

Accession: NM_001145466
基因名称: NCR3
基因别名: 1C7; MALS; CD337; LY117; NKp30
基因描述: Homo sapiens natural cytotoxicity triggering receptor 3 (NCR3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 534 (查看编码区序列)
翻译后氨基酸长度: 177 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region compared to variant 1, that results in a frameshift. It encodes isoform b, which has a shorter and distinct C-terminus compared to isoform a.
产品编号 产品名称 载体 规格 价格
G119183 人 NCR3 (NM_001145466) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]